{"title":"Magnetic Beads","description":"\u003cp\u003eMarvelgent magnetic beads combine a functionalized surface with a superparamagnetic core, allowing target molecules to be captured, separated, washed, and recovered quickly with the aid of an external magnetic field. Compared to traditional centrifugation- or filtration-based methods, magnetic bead workflows significantly reduce manual steps, simplify sample handling, and seamlessly support both individual benchtop experiments and high-throughput parallel processing.\u003c\/p\u003e\n\u003cp\u003eBecause they are easy to separate and adaptable to diverse surface chemistries, magnetic beads are widely utilized in:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eProtein purification and isolation\u003c\/li\u003e\n\u003cli\u003eImmunoprecipitation (IP) and co-immunoprecipitation (Co-IP)\u003c\/li\u003e\n\u003cli\u003ePull-down assays\u003c\/li\u003e\n\u003cli\u003eNucleic acid extraction and clean-up\u003c\/li\u003e\n\u003cli\u003eAssay development and diagnostics\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch5\u003e\u003cbr\u003e\u003c\/h5\u003e\n\u003ch3\u003eMarvelgent Magnetic Beads Key features:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProprietary Coating \u0026amp; Surface Chemistry: \u003c\/strong\u003eEngineered to minimize ligand leaching while supporting a wide range of applications and functional formats.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuperparamagnetic Behavior with Rapid Magnetic Response: \u003c\/strong\u003eEnables swift, efficient separation under a magnetic field while preventing unwanted aggregation during normal handling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eScalable Workflow Compatibility: \u003c\/strong\u003eEqually suited for manual, low-throughput bench experiments and automated, plate-based high-throughput workflows.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStringent Quality Control: \u003c\/strong\u003eRigorous manufacturing standards ensure exceptional lot-to-lot consistency, reliable handling, and dependable workflow performance.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003eMagINDEX™ Agarose Magnetic Resin\u003c\/h3\u003e\n\u003cp\u003eThe MagINDEX™ family extends Marvelgent’s core agarose expertise into magnetic formats for fast, convenient, and scalable protein workflows. Built on proprietary PROTEINEX™ agarose bead technology, MagINDEX™ products combine high-performance biomolecule binding with simple magnetic handling and automation compatibility. Typical applications include the affinity purification of tagged proteins, antibody capture, IP, Co-IP, and pull-down assays.\u003c\/p\u003e\n\u003ch4\u003eKey Features of MagINDEX™ Magnetic Resin\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Binding Capacity: \u003c\/strong\u003eUtilizing Marvelgent PROTEINEX™ agarose bead technology, MagINDEX™ beads provide high ligand density to support the efficient capture and purification of even low-abundance protein targets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSimple Handling: \u003c\/strong\u003eThe beads are superparamagnetic, exhibiting magnetic behavior only in the presence of an external magnetic field. This critical property minimizes unwanted clumping and ensures smooth workflow handling during binding, washing, and elution steps.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAutomation-Ready: \u003c\/strong\u003eA rapid magnetic response makes MagINDEX™ beads ideal for automated platforms, reducing manual intervention while enabling multi-well plate screening workflows to increase laboratory throughput.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVersatile Applications: \u003c\/strong\u003e Optimized for IP, Co-IP, and small-scale purification of His-tagged proteins and antibody-related targets.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eScalability \u0026amp; Flexibility: \u003c\/strong\u003ePerforms reliably across volumes ranging from low-microliter samples to higher-milliliter workflows, offering total flexibility for screening, analytical work, and small-scale preparative purification.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eSelected MagINDEX™ Magnetic Resins\u003c\/h4\u003e\n\u003ctable width=\"100%\" style=\"width: 100%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 33%;\"\u003e\u003cstrong\u003eHis-Tagged Fusion Protein Purification\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 33%;\"\u003e\u003cstrong\u003eAntibody Purification\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 34%;\"\u003e\u003cstrong\u003eOther fusion Protein Molecule Purification\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\" style=\"width: 33%;\"\u003e• Ni-NTA\u003cbr\u003e• Ni-Penta\u003cbr\u003e• Ni-IDA\u003c\/td\u003e\n\u003ctd valign=\"top\" style=\"width: 33%;\"\u003e• Protein A\u003cbr\u003e• Protein G\u003cbr\u003e• Protein A\/G\u003cbr\u003e• NHS-Activated resin\u003c\/td\u003e\n\u003ctd valign=\"top\" style=\"width: 34%;\"\u003e• Glutathione\u003cbr\u003e• Anti-DYKDDDDK\u003cbr\u003e• Anti-GFP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003eSilica and Polymer Magnetic Beads\u003c\/h3\u003e\n\u003cp\u003eBeyond our flagship agarose matrix, Marvelgent develops a broad magnetic bead platform designed to serve diverse applications across life science research, bioprocess development, and diagnostics. By expanding our platform to include silica and polymer-based beads, we broaden the compatibility of our solutions across different target types, chemical environments, and operating conditions.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSilica Magnetic Beads: \u003c\/strong\u003eSpecially suited for nucleic acid workflows that require efficient binding and clean recovery under defined buffer conditions. Typical uses include DNA\/RNA extraction, clean-up, concentration, PCR product clean-up, and molecular diagnostic sample preparation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePolymer Magnetic Beads: \u003c\/strong\u003eHighly adaptable for custom surface functionalization and broad assay development needs. Typical uses include biomolecule immobilization, diagnostic assay development, specific target capture, phase separations, and specialized applications requiring tailored surface chemistries.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003ePartner with Marvelgent\u003c\/h3\u003e\n\u003cp\u003eCombining advanced matrix selection, surface engineering, and stringent process control, Marvelgent provides both high-quality off-the-shelf products and tailored OEM solutions for challenging workflows. \u003cbr\u003e\u003cstrong\u003e\u003ca href=\"mailto:%20customer.support@marvelgent.com\"\u003eContact us \u003c\/a\u003efor more information and tell us how we can support you.\u003c\/strong\u003e\u003c\/p\u003e","products":[{"product_id":"magindex-rprotein-a-magnetic-agarose-resin","title":"MagINDEX™ rProtein A Magnetic Agarose, Settled Resin","description":"\u003cp\u003e\u003cstrong\u003eMag\u003cspan style=\"color: #ee8012;\"\u003eINDEX\u003c\/span\u003e\u003c\/strong\u003e™ rProtein A Magnetic Agarose is an affinity chromatography medium designed for rapid, easy, one-step purification of immunoglobulins, notably IgG isotypes, as well as Fc region-containing fusion proteins.\u003c\/p\u003e\n\u003cp\u003eProprietary MagIndex\u003cb\u003e™\u003c\/b\u003e technology facilitates encapsulation of the superparamagnetic core in the mechanically stable Agarose matrix, which is the optimal absorbance for high yield protein purification with minimal background.\u003c\/p\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\n\u003ctd width=\"70%\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Schematic_composition_of_mag_agarose_resins_862e6d64-9839-4cc9-95d6-b8f9f1b47dcf.png?v=1527170756\" alt=\"\"\u003e\u003c\/td\u003e\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe superparamagnetic core has very fast magnetic response in the magnetic field, but no memory after the magnetic force is removed. The agarose-based encapsulation provides a strong shield well protecting the magnetic core in a wide range of reagents that are commonly used in protein purification. Moreover, as an ideal matrix for protein purification, the agarose matrix enables purification of antibodies and Ig fragments with high purity and high capacity, in high throughput screening and various preparative scales.\u003c\/p\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cdiv class=\"video-wrapper\"\u003e\u003ciframe src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/MagIndex_Magnetic_Agarose_Resins-3.mp4?14800512398908436554\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd width=\"50%\" valign=\"top\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eSuperparamagnetic core\u003c\/strong\u003e with fast response to magnetic field\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eLow nonspecific binding\u003c\/strong\u003e for assay accuracy\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eHigh density of the Protein A\u003c\/strong\u003e ligand for optimal yield of antibodies and Ig fragments\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eHigh stability\u003c\/strong\u003e in common buffer systems and detergents\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eProtein A, a bacterial cell wall protein isolated from \u003cem\u003eStaphylococcus aureus\u003c\/em\u003e, binds to the Fc region of most immunoglobulins through interactions with the heavy chain. Native Protein A contains five high affinity IgG binding domains and many other domains with unknown functions.\u003c\/p\u003e\n\u003cp\u003eThe recombinant Protein A is a genetically engineered protein that contains only the five high affinity IgG binding domains. The non-essential domains were removed to minimize nonspecific binding. The recombinant Protein A is produced in \u003ci\u003eE. coli, \u003c\/i\u003eand it essentially binds to immunoglobulins with the same degree of affinity as the native Protein A. rProtein A is capable of binding with high affinity to the Fc region from IgG of several species including human and rabbit.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eProduct Highlights\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eHigh capacity, \u0026gt; 10 mg rabbit IgG \/ mL of settled resins\u003c\/li\u003e\n\u003cli\u003eHigh selectivity for high purity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eApplications\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eQuick isolation of antibodies from sera and ascites fluids\u003c\/li\u003e\n\u003cli\u003ePurification of scFc fragment from cell cultures\u003c\/li\u003e\n\u003cli\u003eDepletion of unwanted antibodies and fragments from sample\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eTech Note\u003c\/span\u003e\u003c\/h4\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"25%\" valign=\"top\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/MagIndex_Protein_A-4.png?14389587024720716232\" alt=\"\"\u003e\u003c\/td\u003e\n\u003ctd valign=\"bottom\"\u003e\n\u003cp\u003e\u003cstrong\u003eRecombinant scFc protein was isolated from cell culture with MagIndex rProtein A Magnetic Agarose resins. \u003c\/strong\u003eBound the scFc protein was eluted with 100 mM Glycine, pH 3.0, denoted by the blue arrow. Fractions were analyzed by SDS-PAGE.\u003c\/p\u003e\n\u003cp\u003eLanes: (L) Culture supernatant; (FT) Flow-through; (E) Elutions 1 and 2.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSample:\u003c\/strong\u003e 10 mL of culture supernatant containing a scFc fragment (20 µg\/mL)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResin:\u003c\/strong\u003e 0.2 mL settle resins of MagIndex Protein A magnetic agarose\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBinding:\u003c\/strong\u003e 45 min at room temperature\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWashing:\u003c\/strong\u003e 4 mL binding buffer\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eElution:\u003c\/strong\u003e Incubate in 100 mM Glycine, pH 3.0 for 10 min. Repeat 3 times\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eProduct Details\u003c\/h5\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"200\"\u003e\u003cstrong\u003eLigand\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecombinant protein A containing only Ig binding domains\u003cem\u003e\u003cbr\u003e\u003c\/em\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBinding capacity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;10 mg rabbit IgG\/mL medium\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eMatrix\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCross-linked agarose beaded particles containing the superparamagnetic core, supplied as a 20% slurry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParticle size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 μm - 100 μm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003epH stability\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003eLong term: pH 2 - 9;\u003c\/p\u003e\n\u003cp\u003eShort term: pH 2 - 11\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage temperature\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 - 8°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage buffer\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePBS containing 0.01% Tween-20 and 0.02% NaN\u003csub\u003e3\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eProduct is shipped at ambient temperature. Upon receipt store at 2 - 8°C. Do not Freeze.\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e   \u003cimg alt=\"Keep refrigerated\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/icon-Keep-refrigerated_95fa1867-1f0d-47e6-823a-8a0008076e21_small.png?12332456762384261517\" style=\"float: none;\"\u003e   \u003cimg alt=\"Do not freeze\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/icon-Do-not-freeze_2_small.png?12332456762384261517\" style=\"float: none;\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eDocuments\u003c\/h5\u003e\n\u003ch4\u003eTechnical Note\u003c\/h4\u003e\n\u003cp\u003e🗎    \u003ca title=\"Comparison of binding characteristics of immunoglobulin-binding proteins\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Table_Binding_characteristics_of_immunoglobulin-binding_proteins.pdf?6231220717744860621\" rel=\"noopener noreferrer\" target=\"_blank\"\u003eComparison of Binding Characteristics of Immunoglobulin-Binding Proteins\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Marvelgent Biosciences Inc","offers":[{"title":"2 mL","offer_id":6599808221223,"sku":"11-0271-002","price":225.0,"currency_code":"USD","in_stock":true},{"title":"5 mL","offer_id":6600507916327,"sku":"11-0271-005","price":491.0,"currency_code":"USD","in_stock":true},{"title":"10 mL","offer_id":6600507949095,"sku":"11-0271-010","price":710.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/products\/MagIndex_Protein_A.png?v=1525138379"},{"product_id":"magindex-rprotein-a-g-magnetic-agarose-settled-resin","title":"MagINDEX™ rProtein A\/G Magnetic Agarose, Settled Resin","description":"\u003cp\u003e\u003cstrong\u003eMag\u003cspan style=\"color: #ee8012;\"\u003eINDEX\u003c\/span\u003e\u003c\/strong\u003e™ rProtein A\/G Magnetic Agarose is an affinity chromatography medium designed for rapid, easy, one-step purification of a wide range of immunoglobulins, as well as Fc region-containing fusion proteins.\u003c\/p\u003e\n\u003cp\u003eProprietary MagIndex\u003cb\u003e™\u003c\/b\u003e technology facilitates encapsulation of the superparamagnetic core in the mechanically stable Agarose matrix, which is the optimal absorbance for high yield protein purification with minimal background.\u003c\/p\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\n\u003ctd width=\"70%\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Schematic_composition_of_mag_agarose_resins_862e6d64-9839-4cc9-95d6-b8f9f1b47dcf.png?v=1527170756\"\u003e\u003c\/td\u003e\n\u003ctd width=\"15%\"\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThe superparamagnetic core has very fast magnetic response in the magnetic field, but no memory after the magnetic force is removed. The agarose-based encapsulation provides a strong shield well protecting the magnetic core in a wide range of reagents that are commonly used in protein purification. Moreover, as an ideal matrix for protein purification, the agarose matrix enables purification of antibodies and Ig fragments with high purity and high capacity, in high throughput screening and various preparative scales.\u003c\/p\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cdiv class=\"video-wrapper\"\u003e\u003ciframe src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/MagIndex_Magnetic_Agarose_Resins-3.mp4?14800512398908436554\"\u003e\u003c\/iframe\u003e\u003c\/div\u003e\n\u003c\/td\u003e\n\u003ctd valign=\"top\" width=\"50%\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eSuperparamagnetic core\u003c\/strong\u003e with fast response to magnetic field\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eLow nonspecific binding\u003c\/strong\u003e for assay accuracy\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eHigh density of the Protein A\/G\u003c\/strong\u003e ligand for optimal yield of antibodies and Ig fragments\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"color: #444444;\"\u003e\u003cstrong\u003eHigh stability\u003c\/strong\u003e in common buffer systems and detergents\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eProtein A, a bacterial cell wall protein isolated from \u003cem\u003eStaphylococcus aureus\u003c\/em\u003e, binds to the Fc region of most immunoglobulins through interactions with the heavy chain. Native Protein A contains five high affinity IgG binding domains and many other domains with unknown functions. While the native protein G has 3 IgG binding domains as well as sites for albumin and cell-surface binding, recombinant protein G has only Ig recognition domains but no other non-specific sequences. \u003c\/p\u003e\n\u003cp\u003eRecombinant Protein A\/G is a recombinant chimeric protein that is composed of the IgG binding domains of both Protein A and Protein G. rProtein A\/G contains five binding domains from Protein A and two from Protein G. The binding of rProtein A\/G is less pH-dependent than Protein A, but otherwise has the additive properties of Protein A and G. Therefore, rProtein A\/G is ideal for binding the broadest range of IgG subclasses from rabbit, mouse, human and other mammalian samples.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eProduct Highlights\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eHigh capacity, \u0026gt; 10 mg rabbit IgG \/ mL of settled resins\u003c\/li\u003e\n\u003cli\u003eHigh selectivity for high purity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eApplications\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eQuick isolation of antibodies from sera and ascites fluids\u003c\/li\u003e\n\u003cli\u003ePurification of recombinant antibody or scFc fragment from cell cultures\u003c\/li\u003e\n\u003cli\u003eDepletion of unwanted antibodies and fragments from sample\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eProduct Details\u003c\/h5\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\" width=\"200\"\u003e\u003cstrong\u003eLigand\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eRecombinant chimeric protein A\/G containing only Ig binding domains\u003cem\u003e\u003cbr\u003e\u003c\/em\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eBinding capacity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;10 mg rabbit IgG\/mL medium\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003eMatrix\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCross-linked agarose beaded particles containing the superparamagnetic core, supplied as a 20% slurry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eParticle size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e30 μm - 100 μm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd valign=\"top\"\u003e\u003cstrong\u003epH stability\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp\u003eLong term: pH 2 - 9;\u003c\/p\u003e\n\u003cp\u003eShort term: pH 2 - 11\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage temperature\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2 - 8°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage buffer\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePBS containing 0.01% Tween-20 and 0.02% NaN\u003csub\u003e3\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eProduct is shipped at ambient temperature. Upon receipt store at 2 - 8°C. Do not Freeze.\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e   \u003cimg style=\"float: none;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/icon-Keep-refrigerated_95fa1867-1f0d-47e6-823a-8a0008076e21_small.png?12332456762384261517\" alt=\"Keep refrigerated\"\u003e   \u003cimg style=\"float: none;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/icon-Do-not-freeze_2_small.png?12332456762384261517\" alt=\"Do not freeze\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eDocuments\u003c\/h5\u003e\n\u003ch4\u003eTechnical Note\u003c\/h4\u003e\n\u003cp\u003e🗎    \u003ca rel=\"noopener noreferrer\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Table_Binding_characteristics_of_immunoglobulin-binding_proteins.pdf?6231220717744860621\" title=\"Comparison of binding characteristics of immunoglobulin-binding proteins\" target=\"_blank\"\u003eComparison of Binding Characteristics of Immunoglobulin-Binding Proteins\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Marvelgent Biosciences Inc","offers":[{"title":"2 mL","offer_id":12406185754667,"sku":"11-0273-002","price":376.0,"currency_code":"USD","in_stock":true},{"title":"5 mL","offer_id":12406185787435,"sku":"11-0273-005","price":826.0,"currency_code":"USD","in_stock":true},{"title":"10 mL","offer_id":12406185820203,"sku":"11-0273-010","price":1207.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/products\/MagIndex_Protein_A_d9a5f606-cc94-42ef-9a01-9a1543202424.png?v=1528207075"},{"product_id":"magindex-ni-nta-magnetic-agarose-settled-resin","title":"MagINDEX™ Ni NTA Magnetic Agarose, Settled Resin","description":"\u003cp\u003e\u003cstrong\u003eMagINDEX™ Ni-NTA Magnetic Agarose Beads\u003c\/strong\u003e are high-capacity affinity beads engineered for the rapid purification and screening of 6xHis-tagged recombinant proteins. Built on Marvelgent’s proprietary agarose microsphere and surface chemistry platform, these beads combine the high-performance binding of Ni-NTA resin with the speed and simplicity of magnetic separation.\u003cbr\u003eMagnetic bead-based purification streamlines sample processing by eliminating column packing, centrifugation, and gravity-flow handling. Target proteins are captured directly from clarified lysates—whether from bacterial, insect, or mammalian sources—then rapidly separated, washed, and eluted. This format is ideal for:\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid purification\u003c\/strong\u003e of His-tagged proteins (complete in under an hour).\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eParallel processing\u003c\/strong\u003e of multiple samples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmall sample volumes \u003c\/strong\u003ewhere loss must be minimized.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAutomation-compatible workflows\u003c\/strong\u003e where easy handling and reproducibility are essential.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eProduct Highlights\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProprietary Agarose Coating\u003c\/strong\u003e \u003cbr\u003eOur unique coating technology minimizes magnetic particle shedding and leaching. This ensures maximum bead integrity without compromising the rapid magnetic responsiveness required for efficient capture and elution.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptimized Surface Chemistry \u003c\/strong\u003e\u003cbr\u003eEngineered for efficient ligand coupling and robust Ni-NTA presentation, our surface chemistry provides enhanced capacity for His-tagged proteins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid Superparamagnetic Response \u003c\/strong\u003e\u003cbr\u003eThe beads respond to magnetic fields in \u0026lt; 2 seconds. This enables quick, clean separation, reduced hands-on time, and efficient processing of multiple samples.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuperior Purity \u003c\/strong\u003e\u003cbr\u003eBy significantly reducing non-specific binding, the optimized MagINDEX™ surface ensures high-purity results in every eluate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVersatile Workflow Compatibility \u003c\/strong\u003e\u003cbr\u003eCompatible with standard tubes, multi-well plates, and automated magnetic separation platforms. This flexibility supports everything from individual research to high-throughput screening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBroad Buffer Compatibility \u003c\/strong\u003e\u003cbr\u003eStable in a wide range of common purification buffers, including conditions for both native and denaturing His-tag purification.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStringent QC \u0026amp; Lot-to-Lot Consistency\u003c\/strong\u003e \u003cbr\u003eEach lot is manufactured under highly controlled conditions and tested against rigorous quality standards to ensure reproducible performance across every experiment.\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ctable style=\"width: 100%; background-color: rgb(230, 230, 230);\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 40%;\"\u003e\u003ciframe src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/MagIndex_Magnetic_Agarose_Resins-3.mp4?14800512398908436554\"\u003e\u003c\/iframe\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 60%;\"\u003eThe superparamagnetic core provides an exceptionally fast response to magnetic fields, ensuring rapid separation with no residual magnetism once the field is removed. Our proprietary agarose-based encapsulation provides a robust shield that protects the magnetic core across a wide range of common protein purification reagents. This specialized design ensures high chemical stability while minimizing non-specific binding for superior sample purity.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"color: #3d85c6;\"\u003eApplications\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRapid purification \u003c\/strong\u003eof His-tagged recombinant proteins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSmall-scale expression screening \u003c\/strong\u003eto identify high-yield clones.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh-throughput purification \u003c\/strong\u003efrom bacterial, insect, or mammalian lysates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePull-down assays\u003c\/strong\u003e using His-tagged bait proteins to study molecular interactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNative or denaturing purification\u003c\/strong\u003e (refer to specifications for compatible agent ranges).\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #666666;\"\u003e*Note: No significant decrease in yield after 8 repetitive uses of resin when recommended buffers are used. Refer to Product Details for compatible reagents.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Ni_NTA_magnetic_agarose2_255d0ddd-ed6f-43c0-8a90-139f30da1ffd.png?v=1778436974\" alt=\"\" width=\"237\" height=\"342\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFigure 1. Manual purification of an 80 kDa monomeric recombinant protein. \u003c\/strong\u003eAn 80 kDa monomeric His-tagged protein was purified from 50 mL of eukaryotic cell culture spent media using 4 mL of MagINDEX™ Ni-NTA Magnetic Agarose Beads. The sample was incubated for 30 minutes at room temperature with manual magnetic separation. The purified product was eluted with 250 mM imidazole and analyzed by SDS-PAGE under both reducing (+DTT) and non-reducing conditions. The results confirm high-yield recovery and the expected monomeric state of the target protein. Lane 1: Spent medium; Lane 2: Flow-through; Lane 3: Eluate (+DTT); Lane 4: Eluate (non-reduced).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Ni_NTA_magnetic_agarose3.png?v=1778436977\" style=\"display: block; margin-left: auto; margin-right: auto;\" width=\"423\" height=\"288\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFigure 2. Automated high-throughput purification of His-tagged nanobodies. \u003c\/strong\u003eHis6-tagged nanobody clones (1–10; ~15 kDa) were expressed in HEK293 cells. Spent media (2 mL) were incubated with 800 µL of MagINDEX™ Ni-NTA Magnetic Agarose Beads for 30 minutes at room temperature using an automated magnetic separation platform. Samples were eluted with 250 mM imidazole and analyzed by SDS-PAGE. The gel demonstrates consistent recovery and high purity across all ten clones.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch5\u003eProduct Details\u003c\/h5\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eLigand\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003eNickel\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eBinding capacity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003e40 mg 6xHis-tagged protein\/mL medium\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eMatrix\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003eSuperparamagnetic agarose beads\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eParticle size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003e30 μm - 100 μm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eConcentration\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003e20% suspension\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\" valign=\"top\"\u003e\u003cstrong\u003eChemical compatibility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eReducing agents\u003c\/span\u003e:\u003cbr\u003e5 mM DTE, 0.5-1 mM DTT, 20 mM β-mercaptoethanol, 5 mM TCEP, 10 mM reduced glutathione (GSH)\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eDenaturing agents\u003c\/span\u003e:\u003cbr\u003e8 M urea, 6 M Gua-HCl (Tested for one week at 40°C)\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eDetergents\u003c\/span\u003e:\u003cbr\u003e2% Triton™ X-100 (nonionic), 2% Tween™ 20 (nonionic), 2% NP-40 (nonionic), 2% cholate (anionic), 1% CHAPS (zwitterionic)\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eOther additives\u003c\/span\u003e:\u003cbr\u003e500 mM imidazole, 20% ethanol, 50% glycerol, 100 mM Na\u003csub\u003e2\u003c\/sub\u003eSO4, 1.5 M NaCl, 1 mM EDTA, 60 mM citrate\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"text-decoration: underline;\"\u003eCommonly used buffer:\u003c\/span\u003e\u003cbr\u003e50 mM sodium phosphate (pH 7.4), 100 mM Tris-HCl (pH 7.4), 100 mM Tris-acetate (pH 7.4), 100 mM HEPES (pH 7.4), 100 mM MOPS (pH 7.4), 100 mM sodium acetate (pH 4)\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eStorage temperature\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003e2 - 8°C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 25%;\"\u003e\u003cstrong\u003eStorage buffer\u003cbr\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"width: 75%;\"\u003e1x PBS containing 20% ethanol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eProduct is shipped at ambient temperature. Upon receipt store at 2 - 8°C. Do not Freeze.\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e   \u003cimg style=\"float: none;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/icon-Keep-refrigerated_95fa1867-1f0d-47e6-823a-8a0008076e21_small.png?12332456762384261517\" alt=\"Keep refrigerated\" width=\"52\" height=\"50\"\u003e   \u003cimg height=\"30\" width=\"52\" style=\"float: none;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/icon-Do-not-freeze_2_small.png?12332456762384261517\" alt=\"Do not freeze\"\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e \u003c\/p\u003e","brand":"Marvelgent Biosciences Inc","offers":[{"title":"2 mL","offer_id":42661596266539,"sku":"11-0226-002","price":165.0,"currency_code":"USD","in_stock":true},{"title":"10 mL","offer_id":42661497176107,"sku":"11-0226-010","price":750.0,"currency_code":"USD","in_stock":true},{"title":"100 mL","offer_id":42661497241643,"sku":"11-0226-100","price":5250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/files\/Ni-NTA_magnetic_beads-4.png?v=1774387549"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0985\/1250\/collections\/Marvelgent_website_icon_-_magnetic_beads2.png?v=1781630377","url":"https:\/\/marvelgent.com\/collections\/magnetic-resin-technologies\/ligand-functional-group_recombinant-protein-g.oembed","provider":"Marvelgent Biosciences","version":"1.0","type":"link"}